Naturasp is a meticulously formulated dietary supplement designed to aid in pain management and the alleviation of febrile episodes. With a foundation of natural White Willow Bark Extract, this product is rich in anti-inflammatory compounds such as salicin, which is known for its ability to relieve pain from various causes. Beyond its analgesic properties, Willow Bark is also a natural antipyretic, helping to reduce fever, while supporting cardiovascular health by improving blood circulation and promoting blood fluidity.
The formula is further enhanced with Rosehip Extract, which is a powerful antioxidant and vitamin booster due to its high vitamin C content. This makes it an ideal complement for immune system support.
What truly sets Naturasp apart is its holistic formulation and the unique production method, which involves lactic fermentation of biological materials followed by atomization. This innovative process endows the capsules with soothing and regenerative properties for the intestinal mucosa, offering significant anti-inflammatory, antioxidant, and antimicrobial effects, by inhibiting the growth of harmful microorganisms within the intestinal tract. These properties, in turn, support and enhance overall immune health. Through the fermentation process, the product acquires prebiotic, probiotic, and postbiotic properties, which not only balance the intestinal microbiota but also modulate the immune response, further amplifying the anti-inflammatory, antioxidant, analgesic, cardioprotective, antipyretic, and adaptogenic effects of the extracts it contains.
In today’s fast-paced and stressful world, managing inflammation and protecting the immune and cardiovascular systems have become more critical than ever. Our increasingly disordered diets—characterized by irregular meals, poor food combinations, processed foods, and nutrient deficiencies—often exacerbate inflammatory states within the body. These unhealthy dietary patterns, combined with exposure to toxins, additives, and nutritional imbalances (such as an excessive omega-6 to omega-3 ratio, refined carbohydrates, and saturated fats), elevate the risk of chronic inflammation. Moreover, our intestinal microbiota faces constant strain due to the widespread presence of antibiotic residues in animal products and pesticides in plant-based foods. The alarming rise of microplastics in our diet is also a growing concern, with profound negative impacts on overall health.
These stressors—along with insufficient physical activity, dehydration, poor-quality sleep, and harmful lifestyle choices such as excessive alcohol consumption, smoking, and improper medication use—lead to oxidative stress and further exacerbate inflammatory processes in the body. Over time, these factors disrupt the balance of gastric and intestinal microbiota, negatively impacting digestion, mental health, and, most importantly, the immune response.
Lactic Fermentation and Its Health Benefits
Lactic fermentation is a natural process where lactic acid bacteria convert sugars in foods into lactic acid, which acts as a natural preservative, extending the shelf life of foods and imparting a distinct tangy flavor. This fermentation process is common in foods such as yogurt, cheese, and pickled vegetables. Beyond its role in preservation, lactic fermentation also enhances the nutritional value and sensory qualities—flavor, texture, and overall organoleptic properties—of foods.
During fermentation, beneficial lactic acid bacteria, particularly Lactiplantibacillus plantarum, metabolize carbohydrates and produce vital short-chain fatty acids, B-complex vitamins, and phenolic compounds like quercetin and luteolin, all of which have important health benefits. Foods subjected to lactic fermentation are enriched with prebiotics, probiotics, and postbiotics, which support the balance of intestinal flora, enhance immune function, and reduce inflammation.
A significant benefit of lactic fermentation with L. plantarum is the documented reduction in the immunoreactivity of allergenic foods such as milk, soy, and wheat, making them more tolerable for sensitive individuals. Additionally, L. plantarum produces bacteriocins—small proteins with potent antimicrobial activity—that inhibit the growth of harmful bacteria, including Salmonella, E. coli, and Staphylococcus aureus. Furthermore, the fermentation process reduces the presence of aflatoxins, harmful substances often found in contaminated foods.
Research on L. plantarum has revealed an array of health-promoting properties, including antioxidant effects (through the generation of phenolic compounds and enzymes like superoxide dismutase—SOD), cardio- and hepatoprotective properties, hypoglycemic benefits (by improving insulin sensitivity and regulating blood sugar levels), and enhanced vitamin production (notably folate—vitamin B9, riboflavin—vitamin B2, and vitamins B12, K, and C). Fermented foods also show improved mineral content, such as calcium, magnesium, iron, and selenium, due to the breakdown of plant materials by L. plantarum.
The immunomodulatory and antimicrobial properties of lactic fermentation extend to promoting anti-inflammatoryresponses and protecting the body against viral and bacterial infections. Additional benefits include antidepressant and anxiolytic effects, attributed to the modulation of intestinal microbiota and the enhancement of serotonin production, as well as anti-obesity effects through the regulation of appetite, improvement of lipid metabolism, and modulation of inflammation.
Through the lactic fermentation of biological materials in the Naturasp formula, we have achieved a product with superior nutritional value and health benefits. The fermentation process increases the bioavailability and concentration of active compounds, including polyphenols, flavonoids, organic acids, short-chain fatty acids, prebiotics, probiotics, postbiotics, vitamins, minerals, antibacterial and antiviral agents, and antioxidant enzymes. This ensures a potent, natural solution to combat the factors that negatively impact health and overall well-being.
With Naturasp, you’re choosing an innovative, holistic approach to supporting your cardiovascular and immune healthwhile effectively managing pain, inflammation, and fever.
Naturasp, also known as the “Vegetal Aspirin,” is a natural extract derived from White Willow bark (Salix alba). It is an effective adjunct in reducing fever, relieving pain of various origins, reducing inflammation, improving peripheral circulation, and reducing cellular division errors. Additionally, this natural integral extract contributes to blood thinning, acting as a potent anti-platelet aggregator, thereby promoting better oxygenation of the body. Modern studies have shown the efficacy of a White Willow extract regimen in alleviating lower back pain. Furthermore, since it is not a synthetic product and contains calcium carbonate, the White Willow bark extract, or the “vegetal aspirin” in Naturasp, has a gentler effect on the stomach and reduced antithrombotic action compared to traditional formulas, with a lower risk of inducing bleeding.
The primary active compounds in White Willow bark are salicylates such as Salicin and Salicylic Acid. Besides Willow, salicylic derivatives are abundantly found in berries, meadowsweet, alfalfa, pansies (Viola tricolor), poplar, birch, plants from the genus Spiraea, and some spices, typically serving as phytohormones. Among the foods richest in salicylic compounds are various fruits and vegetables, nuts, sweet potatoes, olive oil, and even beer. Salicin is a phenolic glycoside and a biosynthetic precursor of salicylic aldehyde. It was first isolated in 1824 by two Italian pharmacists from Verona, Bartolomeo Rigatelli, who named the compound a “very bitter antipyretic salt,” and Francesco Fontana, who coined the term “salicin” from the Latin name for Willow (Salix). In 1828, German pharmacologist Johann Andreas Buchner also isolated salicin from Willow bark. However, the first scientist to synthesize a pure (crystallized) form of salicin was the French pharmacist Pierre-Joseph Leroux in 1829.
Regarding Salicylic Acid, it was first obtained in 1838 by the Italian chemist Raffaele Piria from salicin. The following year (1839), this acid was also isolated from meadowsweet extract (Filipendula ulmaria) by German researchers. Salicylic acid derivatives, known as salicylates, are highly useful in blood thinning by inhibiting the secretion of thromboxanes and prostaglandins. These compounds are also involved in the body’s mechanisms to limit inflammatory processes. Blood thinning, within normal limits, is associated with the proper functioning of the cardiovascular system. Salicylic acid is also widely used externally and is often labeled as BHA in many cosmetic products for treating acne and in various exfoliants, as well as products intended to combat warts, calluses, dandruff, psoriasis, seborrheic dermatitis, and other dermatological conditions.
Finally, in 1853, the French chemist Charles Frédéric Gerhardt synthesized acetylsalicylic acid for the first time, using sodium salicylate and acetyl chloride, but in an impure and unstable form. Forty-four years later (1897), acetylsalicylic acid was synthesized again in its pure form, derived from salicin extracted from meadowsweet (then called Spiraea ulmaria) by the German chemist Felix Hoffman, an employee of Bayer, using a process created by his colleague Arthur Eichengrün. Interestingly, although Eichengrün’s extraction process was proven in 1999, Bayer continues to credit Hoffman as the one who synthesized the first pharmacologically useful form of this compound. In 1899, acetylsalicylic acid synthesized by Bayer laboratories was patented and introduced to the pharmaceutical market under the name “Aspirin.” This name was derived by combining the prefix “a(cetyl)” with the scientific name of the plant “Spir(aea)”from which the medicine was synthesized, and the common chemical suffix “-in.”
Discovered over 120 years ago, Aspirin is today the most widely used medication in the world and is included on the World Health Organization’s (WHO) list of essential medicines. Classified as a nonsteroidal anti-inflammatory drug (NSAID), Aspirin is often prescribed long-term to patients with cardiovascular problems, offering a protective effect, particularly for those who have suffered from heart attacks, and for preventing strokes or treating rheumatic, autoimmune, or psychiatric conditions. Recent studies have also suggested a potential protective effect against uncontrolled cell multiplication through mechanisms involving necrosis and apoptosis induction. Unfortunately, despite its health benefits, synthetic acetylsalicylic acid—or Aspirin—is associated with a range of side effects, such as gastrointestinal mucosal irritation and the stimulation of vitamin C depletion in the body.
For these reasons, the balanced natural formula of Naturasp addresses these side effects by combining White Willow bark extract (Salix alba) with Vitacan® (an extract from Rosehip fruits—Rosa canina), rich in polyphenols and vitamin C. This combination of two complementary health-promoting extracts allows for the beneficial effects of natural aspirin (analgesic, antipyretic, depurative, anti-inflammatory) without depleting the body’s vitamin C reserves. Moreover, recent studies have shown greater tolerance of salicylic acid and its derivatives (aspirin) on the gastroduodenal mucosa when associated with vitamin C and/or polyphenols.
White Willow (Salix alba), is a deciduous, dioecious tree from the Salicaceae family. This tree thrives near water sources and grows in floodplains and wetlands in both lowland and hilly regions. In Romania, White Willow grows spontaneously in areas like the Danube floodplain, along rivers and lakes, and is often cultivated near villages for its utility in construction (e.g., woven fences) and in the textile industry(e.g., tanning hides or dyeing textiles). It is also valued in cities for aesthetic purposes.
Willow bark preparations have a history of use dating back over 6,000 years. The bark of this tree was often chewed to reduce fever or alleviate pain. The phytotherapeutic properties of Willow bark were described in antiquity by Dioscorides in his work De Materia Medica. Additionally, Galen, Pliny the Elder, and Hippocrates mentioned its health-promoting properties. There are also references in ancient texts from the Sumerians, Assyrians, and Egyptians about the beneficial effects of Willow and Poplar bark derivatives. When not consumed directly, Willow bark was macerated in alcohol to create tinctures. Native American tribes, such as the Cherokee, used Willow bark and leaves in infusions. Generally, for preparation, 2-3-year-old young branches and sometimes leaves collected in spring-summer are used.
In modern phytotherapy, Willow bark derivatives are considered highly effective for pain relief from rheumatic, muscular, menstrual, or headache pain. This analgesic and anti-inflammatory action is due to the inhibition of prostaglandin synthesis by salicin derivatives. Additionally, the tannins in Willow bark possess astringent and bitter tonic properties. Willow bark extracts are also useful for reducing fever and calming the nervous system. They also have vasodilatory properties and stimulate peripheral circulation. Thus, Willow bark extract is a powerful analgesic and anti-inflammatory agent, particularly indicated for reducing fever and alleviating pain of various origins. It supports the health of muscles and joints and revitalizes the nervous system and the entire body. Externally, it protects the skin and hair, inhibiting excessive sweating and sebum secretion.
Moreover, the active compounds in Willow bark (e.g., phenolic glycosides/salicylates such as salicin, saligenol, salireposide, piceoside, populoside; tannins, gallotannins, procyanidins, flavonoids, resins, oxalates, vitamins, and mineral salts) contribute to blood thinning, maintaining normal cellular division, and calming the overworked nervous system. Thus, the virtues of Willow bark products include anti-inflammatory, analgesic, nervous system sedative, bitter tonic, anticoagulant, antipyretic, vasodilatory, antitumor, antirheumatic, and diuretic actions. Externally, Willow bark derivatives have analgesic, antiseptic, anti-inflammatory, mild hemostatic, cicatrizing, antiseborrheic, anti-acne, and anti-sweating actions.
Vitacan®, or highly bioavailable concentrated Rosehip extract, is rich in vitamin C and bioflavonoids, which are necessary to combat free radicals and oxidative stress. The dry extract is obtained from cold-pressed juice of fresh or frozen Rosehip fruits (Rosa canina). The active compounds in the biological material, as well as new ones generated during lactic fermentation with highly active strains of Lactiplantibacillus plantarum, are preserved. The final step is the atomization of the extract, ensuring that the fine particles of fermented juice are encapsulated in maltodextrin. This process transforms the liquid extract into a dry form that is easy to dose, encapsulate, and administer. Through atomization, the active compounds generated during lactic fermentation of the Rosehips are better protected from environmental factors (e.g., air, light, temperature, humidity) and endogenous factors (e.g., gastric juice). Thus, the stability of the extract over time is improved, and its health-promoting effects are enhanced by increasing biological activity and ensuring the transport of a higher percentage of active compounds to the intestinal level.
Vitamin C (ascorbic acid) is an essential micronutrient for life. It is necessary for the synthesis of collagen in the skin, bones, teeth, gums, and cartilage. Additionally, it stimulates the absorption of iron and, along with vitamins A and E, has a strong antioxidant action, fighting against free radicals and oxidative stress.
Vitamin C also helps regenerate the reduced forms of vitamin E, restoring its antioxidant activity. Another important role of vitamin C is to strengthen the immune system and assist in the biosynthesis of stress-adaptation hormones. An adequate intake of vitamin C (at least 260 mg/day) helps shorten recovery periods and balances the immune system. Like other vitamins, vitamin C is involved in cellular energy metabolism, providing the body with an extra boost of energy during periods of exhaustion.
Unfortunately, this vitamin is easily excreted from the human body, and the body cannot synthesize the necessary amounts of vitamin C. Exposure to various stressors, such as smoking (active or passive), unbalanced lifestyles, and certain medications (e.g., aspirin, contraceptives), accelerates the elimination of this nutrient or reduces its absorption from dietary sources. Additionally, vitamin C is easily destroyed by oxidation and thermal treatment (e.g., cooking), which reduces its intake from foods that are not consumed fresh or raw. Therefore, in the modern diet, based on highly processed foods, the body may not receive an adequate supply of vitamin C.
The special formula of Naturasp provides the body with an easily absorbable source of vitamin C. The Rosehip extract, one of the richest natural sources of vitamin C, ensures the high bioavailability of this vitamin. In Naturasp, ascorbic acid is present in its natural food matrix, making it more easily absorbed and utilized by the body.
Rosehip (Rosa canina), is a thorny shrub with a taproot and a height ranging from 1 to 5 meters. It belongs to the Rosaceae family and is considered the ancestor of many rose varieties. It is commonly found along fences, roadsides, pastures, and forests, growing spontaneously in Europe, western Asia, and northwest Africa. In Europe, Rosehip is appreciated for its aromatic and slightly tart fruits. Along with black currants, blackberries, and blueberries, Rosehips are a natural source of vitamins, antioxidants, and anti-inflammatory compounds.
Most commonly, Rosehips, as well as their leaves, flowers, and bark, are used as they are or for creating dietary supplements (e.g., tinctures, teas, syrups, and dry extracts).
According to phytotherapy studies, Rosehip fruits (Cynosbati fructus) are useful in restoring the balance of intestinal microbiota (regulating stool frequency and consistency) and in detoxifying the body through the gastrointestinal tract, kidneys, and sweating. They have antiseptic properties for the digestive and urinary tracts, limiting the growth of potentially pathogenic species like E. coli or Candida spp. by precipitating proteins and exhibiting antilithic properties (preventing kidney stones). Furthermore, Rosehips have astringent, cholagogue, choleretic, vermifuge, and vasodilatory effects.
Due to their high content of antioxidants (e.g., polyphenols, bioflavonoids, and vitamin C—approximately 2g per 100g of fruit), Rosehip fruits help mitigate the negative effects of oxidative stress by binding to cellular DNA and limiting the degradation of genetic material. Thus, they have anti-inflammatory and anti-aging effects, protecting cells from premature aging. In short, Rosehip contributes to maintaining the health and flexibility of joints and supports the proper functioning of the immune, respiratory, cardiovascular, musculoskeletal, and digestive systems.
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